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Can we reduce the $C^1(U)$ operation from $AXBXC$ to $AXBX$?

In Quantum Computation and Quantum Information, $C(U) = AXBXC$ where $A=R_z(\beta)R_y(\gamma/2) , B=R_y(-\gamma/2)R_z(-(\delta + \beta)/2), and C=R_z((\delta - \beta)/2)$ . Instead is it possible ...
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How to reduce circuit elements of a decomposed $C^2(U)$ operation?

This question refers to Nielsen and Chuang's Exercise 4.22: Prove that a $C^2(U)$ gate (for any single qubit unitary U) can be constructed using at most eight one-qubit gates, and six controlled-not ...
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Document pessimism about the feasibility of a quantum computer

I'm actually searching two types of documents (could be the same): 1) A synthesis about all the main gap/problems that make the physical realisation of a quantum computer actually infeasible. 2) ...