The answer is yes and no depending on the state it acts upon.
If you perform a CNOT gate on the state $|00\rangle$ with the first qubit being controlled and the second qubit being the target then nothing happens. Thus, the resulting state is not entangled. This is the second circuit in your question.
$$ CX_{0,1} |00\rangle = |00\rangle$$
If you perform the same CNOT gate to the state $|10\rangle$ then the resulting state is $|11\rangle$ which again is a product (not entangled) state.
$$ CX_{0,1} |10\rangle = |11\rangle$$
This is the first circuit you have in your question.
However, if you perform the same CNOT gate to the product (not entangled state) state $|\psi_0 \rangle = \dfrac{ (|0\rangle + |1\rangle) \otimes |0\rangle }{\sqrt{2}} = \dfrac{|00\rangle + |10\rangle}{\sqrt{2}} $ then your result is an entangled state of the form $|\psi \rangle = \dfrac{|00\rangle + |11\rangle}{\sqrt{2}} $. This is also known as the Bell state. So that is,
$$ CX_{0,1} \dfrac{|00\rangle + |10\rangle}{\sqrt{2}} = \dfrac{|00\rangle + |11\rangle}{\sqrt{2}}$$
The corresponding circuit here is:

The Hadamard gate ($H$) brings the initial state $|00\rangle$ to the state $|\psi_0 \rangle = \dfrac{ (|0\rangle + |1\rangle) \otimes |0\rangle }{\sqrt{2}} = \dfrac{|00\rangle + |10\rangle}{\sqrt{2}} $.
So in summary, the resulted state after the application of the CNOT gate is entangled of not is depending what the prior state before the application of the CNOT gate is.
Yes, a circuit that lacks two qubit gates like CNOT gate can't create entanglement state! However, you don't have entanglement just because you have two qubit gates in your circuit.
There are way more entangle states then there are unentangle states so it is not hard to make a circuit to create a state with some degree in entanglement in your system. In fact, if you create a circuit randomly from single and two qubit gates, you will almost surely generate an entangled state.